Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785204 | 0.90 | PARP10 (0.45) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| Hydrazine SCHEMBL3522472 | 0.90 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL335459 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL5395245 | 0.88 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL1648666 | 0.82 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL6331530 | 0.81 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| Pyrrole SCHEMBL9111233 | 0.81 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL9091164 | 0.79 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL7715882 | 0.78 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL15058294 | 0.76 | POLB (0.50) | SMN1; SMN2PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |