Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819242 | 0.93 | KMT2A (0.65) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL29887369 | 0.93 | KMT2A (0.65) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7785379 | 0.88 | KMT2A (0.60) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL3850748 | 0.83 | MAPT (0.63) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL28589510 | 0.82 | SMN1; SMN2 (0.54) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL758414 | 0.81 | MAPT (0.62) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL29886209 | 0.78 | ALDH1A1 (0.65) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL16592667 | 0.78 | ALDH1A1 (0.65) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL7079773 | 0.78 | KMT2A (0.69) | KMT2AALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL1354320 | 0.77 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |