Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266779 | 0.90 | MEN1 (0.35) | NPC1RAB9APOLBHSP90AA1 | |
| SCHEMBL9270532 | 0.90 | NPC1 (0.33) | NPC1RAB9APOLBHSP90AA1 | |
| SCHEMBL8344918 | 0.84 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29708 | 0.83 | NPC1 (0.49) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29350736 | 0.83 | NPC1 (0.49) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL22606176 | 0.81 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL712969 | 0.81 | NPC1 (0.38) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29706577 | 0.81 | NPC1 (0.38) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL7574013 | 0.81 | CYP3A4 (0.39) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL22080465 | 0.80 | NPC1 (0.37) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977219-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-02 | — | — | US | claimed |
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | claimed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| US-5280124-A | Having a phenol structure in position 2 | CIBA-GEIGY CORPORATION (US) | 1994-01-18 | — | — | US | claimed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | claimed |
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |
| US-5436349-A | Photostabilizers for polymers for radiation resistance | CIBA-GEIGY CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| US-5410071-A | Sulfiding with a thiophenolic compound or a thiophenolate in a polar solvent to form a stabilizers for polyphenylene sulfide against UV radiation | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5280124-A | Having a phenol structure in position 2 | CIBA-GEIGY CORPORATION (US) | 1994-01-18 | — | — | US | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0572554-A1 | 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | Ciba SC Holding AG (CH) | 1993-12-08 | — | — | EP | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1992014717-A1 | 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-09-03 | — | — | WO | disclosed |