⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034193 | 1.00 | — | — | |
| SCHEMBL7120379 | 0.85 | — | — | |
| SCHEMBL3970107 | 0.80 | OPRD1 (0.41) | — | |
| SCHEMBL6692977 | 0.80 | OPRD1 (0.41) | — | |
| SCHEMBL290880 | 0.80 | — | — | |
| SCHEMBL327601 | 0.80 | OPRD1 (0.41) | — | |
| Bromide SCHEMBL7969410 | 0.77 | OPRD1 (0.40) | — | |
| SCHEMBL10829080 | 0.77 | KDM4E (0.33) | — | |
| SCHEMBL1489209 | 0.75 | — | — | |
| SCHEMBL88222 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | claimed |
| US-5247096-A | Reaction of maleimide and di-tert-butyl carbonate in the presence of base | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | claimed |
| US-4518799-A | GRIGNARD REAGENTS AND THEIR PREPARATION | THE UPJOHN COMPANY (US) | 1985-05-21 | — | — | US | claimed |
| CN-118240142-A | Cycloolefin copolymer and process for producing cycloolefin copolymer | 歌尔光学科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-104334629-B | Rubber composition for tire tread and pneumatic tire | 住友橡胶工业株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-104334629-A | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER IND | 2015-02-04 | — | — | CN | disclosed |
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |
| US-5247096-A | Reaction of maleimide and di-tert-butyl carbonate in the presence of base | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |