Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 8/20 | 0.41 |
| ▸ | NOS1 | P29475 | 7/20 | 0.41 |
| ▸ | NOS3 | P29474 | 5/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL5050788 | 1.00 | OTC (0.43) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL28404344 | 0.87 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL28404346 | 0.87 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL28066501 | 0.86 | OTC (0.47) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL27902011 | 0.86 | SLC22A16 (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL22127062 | 0.85 | OTC (0.54) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL27504717 | 0.85 | OTC (0.54) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL22127060 | 0.85 | OTC (0.54) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL29366751 | 0.85 | OTC (0.54) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL27504716 | 0.85 | OTC (0.54) | OTCNOS2NOS1NOS3DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1152661-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2001-11-14 | — | — | EP | claimed |
| WO-2000047046-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2000-08-17 | — | — | WO | claimed |
| US-20160287658-A1 | COMPOSITION FOR MOISTURIZING SKIN | AMOREPACIFIC CORPORATION (KR) | 2016-10-06 | — | — | US | disclosed |
| EP-1152661-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000047046-A1 | METHOD FOR INCREASING THE YIELD OF CROP PLANTS PRODUCE BY STIMULATING GERMINATION OF POLLEN GRAINS | LABORATOIRES GOEMAR S.A. (FR) | 2000-08-17 | — | — | WO | disclosed |