Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.73 |
| ▸ | XIAP | P98170 | 11/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785844 | 0.95 | GHSR (0.80) | GHSRXIAPAGTR1PTGER1PTGER3 | |
| SCHEMBL7794451 | 0.94 | GHSR (0.81) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785880 | 0.93 | GHSR (0.73) | GHSRXIAPAGTR1PTGER1PTGER3 | |
| SCHEMBL7786019 | 0.92 | GHSR (0.80) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7795975 | 0.91 | GHSR (0.71) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785735 | 0.91 | GHSR (0.70) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785922 | 0.91 | GHSR (0.78) | GHSRXIAPAGTR1PTGER1PTGER3 | |
| SCHEMBL8329924 | 0.90 | GHSR (0.90) | GHSRXIAPAGTR1PTGER1PTGER3 | |
| SCHEMBL7785883 | 0.90 | GHSR (0.68) | GHSRXIAPAGTR1NPY1R | |
| SCHEMBL7785875 | 0.90 | GHSR (0.70) | GHSRXIAPAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |