Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.46 |
| ▸ | METAP1 | P53582 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 6/20 | 0.40 |
| ▸ | FNTB | P49356 | 6/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559186 | 0.95 | METAP2 (0.50) | METAP2METAP1FNTAFNTBPGGT1B | |
| SCHEMBL7784068 | 0.94 | METAP2 (0.44) | METAP2METAP1FNTAFNTBPGGT1B | |
| SCHEMBL6558505 | 0.93 | METAP2 (0.46) | METAP2METAP1FNTAFNTBPGGT1B | |
| SCHEMBL6559321 | 0.92 | METAP2 (0.42) | METAP2METAP1FNTAFNTBPGGT1B | |
| SCHEMBL7785830 | 0.90 | METAP2 (0.44) | METAP2METAP1 | |
| SCHEMBL6558831 | 0.88 | METAP2 (0.49) | METAP2METAP1 | |
| SCHEMBL6558918 | 0.86 | METAP2 (0.47) | METAP2METAP1BACE1 | |
| SCHEMBL6560877 | 0.86 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL7783697 | 0.85 | METAP2 (0.43) | METAP2METAP1BACE1 | |
| SCHEMBL6559017 | 0.85 | METAP2 (0.47) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140979-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040599-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |