Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630414 | 0.87 | PTPN1 (0.66) | GSK3BPTPN1CES2NOTUM | |
| SCHEMBL27250053 | 0.84 | CES2 (0.52) | CES2NOTUMADCY8ADCY1KCNK3 | |
| SCHEMBL12187811 | 0.83 | PTPN1 (0.56) | GSK3BPTPN1CES2NOTUMMAPT | |
| SCHEMBL5801698 | 0.81 | GSK3B (0.61) | GSK3BPTPN1 | |
| SCHEMBL766117 | 0.81 | NOTUM (0.58) | GSK3BPTPN1CES2NOTUMGPBAR1 | |
| SCHEMBL865889 | 0.81 | PTPN1 (0.58) | GSK3BPTPN1CES2NOTUM | |
| SCHEMBL766063 | 0.79 | GSK3B (0.56) | GSK3BPTPN1CES2MEN1KMT2A | |
| SCHEMBL1189645 | 0.79 | GSK3B (0.51) | GSK3BPTPN1CES2NOTUMADCY8 | |
| SCHEMBL2926459 | 0.78 | TPMT (0.61) | CES2NOTUMADCY8ADCY1KCNK3 | |
| SCHEMBL7786247 | 0.78 | CES2 (0.52) | CES2NOTUMADCY8ADCY1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |