SCHEMBL7786142

SCHEMBL7786142

CCCCCCCCCCCCCCCCCCN(CC(O)CO)C(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.47
FFAR4 Q5NUL3 1/20 0.45
FFAR1 O14842 1/20 0.45
DGKA P23743 1/20 0.41
KDM5A P29375 3/20 0.41
PHF8 Q9UPP1 3/20 0.41
KDM4C Q9H3R0 2/20 0.41
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787364 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3837641 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2495445 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL13936677 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL4145580 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8984841 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL7786496 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3834662 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2639306 0.94 KDM4E (0.42) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2496998 0.94 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251878-B1 TREATING ULTRAVIOLET LIGHT-INDUCED SUPPRESSION OF IMMUNE RESPONSE OF SKIN OF ANIMAL BY CONTACTING SKIN WITH COMPOSITION COMPRISING TAMARIND SEED XYLOGLUCAN OLIGOSACCHARIDES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2001-06-26 US disclosed
US-5653970-A CLEANING COMPOUNDS; COSMETICS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-05 US disclosed
US-5476671-A Skin disorders CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1995-12-19 US disclosed
WO-1995016665-A1 SYNTHETIC CERAMIDES AND THEIR USE IN COSMETIC COMPOSITIONS UNILEVER PLC (GB) 1995-06-22 WO disclosed