SCHEMBL4145580

SCHEMBL4145580

CCCCCCCCCCCCCCCC(=O)N(CCCCCCCCCCCC)CC(O)CO

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.47
FFAR4 Q5NUL3 1/20 0.45
FFAR1 O14842 1/20 0.45
DGKA P23743 1/20 0.41
KDM5A P29375 3/20 0.41
PHF8 Q9UPP1 3/20 0.41
KDM4C Q9H3R0 2/20 0.41
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787364 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3837641 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2495445 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL13936677 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8984841 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL7786142 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL7786496 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3834662 1.00 KDM4E (0.47) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2639306 0.94 KDM4E (0.42) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2496998 0.94 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240948-A1 METHOD FOR PRODUCING COATING KAO CORPORATION (JP) 2023-08-03 US disclosed
US-20230240948-A1 METHOD FOR PRODUCING COATING KAO CORPORATION (JP) 2023-08-03 US disclosed
US-20220031582-A1 OIL-IN-WATER TYPE SUNSCREEN COSMETIC KAO CORPORATION (JP) 2022-02-03 US disclosed
EP-3733160-A1 EMULSIFIED COMPOSITION Kao Corporation (JP) 2020-11-04 EP disclosed
US-20200337953-A1 EMULSIFIED COMPOSITION KAO CORPORATION (JP) 2020-10-29 US disclosed
EP-2662071-B1 COSMETIC comprising a ceramide KAO CORP (JP) 2018-06-20 EP disclosed
US-9339448-B2 Emulsion composition KAO CORPORATION (JP) 2016-05-17 US disclosed
US-9339448-B2 Emulsion composition KAO CORPORATION (JP) 2016-05-17 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
US-9278059-B2 Emulsified cosmetic composition KAO CORPORATION (JP) 2016-03-08 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-8178584-B2 Sphingosines, fatty acid, and oil; improved stability and feel to skin KAO CORPORATION (JP) 2012-05-15 US disclosed
US-20120108661-A1 EMULSIFIED COMPOSITION KAO CORPORATION (JP) 2012-05-03 US disclosed
US-20120108661-A1 EMULSIFIED COMPOSITION KAO CORPORATION (JP) 2012-05-03 US disclosed
US-20110263714-A1 Reverse Vesicle KAO CORPORATION (JP) 2011-10-27 US disclosed
US-20110263714-A1 Reverse Vesicle KAO CORPORATION (JP) 2011-10-27 US disclosed
US-6251878-B1 TREATING ULTRAVIOLET LIGHT-INDUCED SUPPRESSION OF IMMUNE RESPONSE OF SKIN OF ANIMAL BY CONTACTING SKIN WITH COMPOSITION COMPRISING TAMARIND SEED XYLOGLUCAN OLIGOSACCHARIDES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2001-06-26 US disclosed
US-5653970-A CLEANING COMPOUNDS; COSMETICS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-08-05 US disclosed
US-5476671-A Skin disorders CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1995-12-19 US disclosed
WO-1995016665-A1 SYNTHETIC CERAMIDES AND THEIR USE IN COSMETIC COMPOSITIONS UNILEVER PLC (GB) 1995-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220031582-A1 OIL-IN-WATER TYPE SUNSCREEN COSMETIC SUN2, H1-0, CUTA KDM4E 4693/4885DUSP3 4837/4885MEN1 517/4885
US-20230240948-A1 METHOD FOR PRODUCING COATING CUTA, KRT18, S100B KDM4E 250/4885DUSP3 4800/4885MEN1 2776/4885
US-20200337953-A1 EMULSIFIED COMPOSITION SGMS2, SGMS1, CERT1 KDM4E 4176/4885DUSP3 4737/4885MEN1 2457/4885
US-20120108661-A1 EMULSIFIED COMPOSITION CERT1, S1PR4, S1PR3 KDM4E 946/4885DUSP3 4029/4885MEN1 1285/4885
US-20110263714-A1 Reverse Vesicle SGMS1, EXOSC10, SGMS2 KDM4E 1070/4885DUSP3 4696/4885MEN1 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.