Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781660 | 1.00 | TYR (0.42) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL7781665 | 0.99 | TYR (0.40) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL13464690 | 0.83 | TYR (0.50) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL9710376 | 0.83 | TYR (0.50) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL30294101 | 0.83 | TYR (0.50) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL13464625 | 0.83 | TYR (0.50) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL223670 | 0.81 | TYR (0.47) | TYRCYP3A4MAPTMEN1TP53 | |
| SCHEMBL15164264 | 0.80 | RARB (0.55) | CYP3A4MAPTMEN1TP53TSHR | |
| SCHEMBL7788527 | 0.78 | SMN1; SMN2 (0.43) | MAPTMEN1HTTKMT2ANPC1 | |
| SCHEMBL7781638 | 0.78 | SMN1; SMN2 (0.43) | MAPTMEN1HTTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |