Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464625 | 0.98 | TYR (0.50) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL9710376 | 0.98 | TYR (0.50) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL30294101 | 0.98 | TYR (0.50) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL13464690 | 0.98 | TYR (0.50) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL6691430 | 0.94 | TYR (0.47) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL5404668 | 0.86 | PYCR1 (0.47) | PYCR1PDPK1MTNR1BBCAT2KDM1A | |
| SCHEMBL7781665 | 0.82 | TYR (0.40) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL1310295 | 0.81 | PDPK1 (0.41) | PYCR1PDPK1MTNR1BKDM1A | |
| Formaldehyde SCHEMBL27932210 | 0.81 | PDPK1 (0.44) | PYCR1PDPK1MTNR1BBCAT2KDM1A | |
| SCHEMBL7781660 | 0.81 | TYR (0.42) | TYRTSHRMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618101-B1 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| EP-1618101-B1 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| CN-102015964-B | Thiophene derivatives, and LC media containing the same | MERCK PATENT GMBH | 2013-07-17 | — | — | CN | disclosed |
| US-8486297-B2 | Thiophene derivatives, and LC media comprising same | MERCK PATENT GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8486297-B2 | Thiophene derivatives, and LC media comprising same | MERCK PATENT GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8394293-B2 | Thiophene derivatives, and LC media containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-12 | — | — | US | disclosed |
| EP-2398787-B1 | Thiophene derivates and liquid crystal media comprising the same | MERCK PATENT GMBH (DE) | 2013-01-30 | — | — | EP | disclosed |
| EP-2265692-B1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2012-07-04 | — | — | EP | disclosed |
| EP-2265692-B1 | THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME | MERCK PATENT GMBH (DE) | 2012-07-04 | — | — | EP | disclosed |
| EP-1618101-A2 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004076438-A2 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-09-10 | — | — | WO | disclosed |
| US-6737125-B2 | SUCH AS 8,9-DIFLUORO-7-(4-PENTYLPHENYL)-2-PROPYL-2,3-DIHYDRO-1H -CYCLOPENTA(A)NAPHTHALENE; FOR USE IN AUTOMOBILE INTERIORS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-05-18 | — | — | US | disclosed |
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | CLARIANT INTERNATIONAL LTD. | 2003-06-12 | — | — | US | disclosed |
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
| US-5637257-A | LIQUID CRYSTAL DISPLAYING | MERCK PATENT GESELLSCHAFT MLT BESCHRANKTER HAFTUNG (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5482653-A | FOR LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-09 | — | — | US | disclosed |
| WO-1990015113-A1 | FLUORO-CHLORO-BENZENE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108684-A1 | Such as 8,9-difluoro-7-(4-pentylphenyl)-2-propyl-2,3-dihydro-1H -cyclopenta(a)naphthalene; for use in automobile interiors | SCO2, CYP2F1, OGFOD1 | TYR 3555/4885TSHR 4358/4885MEN1 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.