⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786273 | 1.00 | — | — | |
| SCHEMBL7785789 | 0.79 | — | — | |
| SCHEMBL7785787 | 0.79 | — | — | |
| SCHEMBL7785774 | 0.77 | NPSR1 (0.42) | — | |
| SCHEMBL21974585 | 0.77 | NPSR1 (0.42) | — | |
| SCHEMBL7785776 | 0.77 | NPSR1 (0.42) | — | |
| SCHEMBL5069189 | 0.76 | — | — | |
| SCHEMBL1421463 | 0.75 | EP300 (0.37) | — | |
| SCHEMBL221551 | 0.73 | — | — | |
| SCHEMBL221550 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971919-B1 | PROCESS FOR PREPARATION OF 4H-4-OXO-QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES | ABBOTT LAB (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0971919-A1 | PROCESS FOR PREPARATION OF 4H-4-OXO-QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES | Abbott Laboratories (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998038191-A1 | PROCESS FOR PREPARATION OF 4H-4-OXO-QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1998-09-03 | — | — | WO | disclosed |
| US-5693813-A | Process for preparation of 4H-4-oxo-quinolizine-3-carboxylic acid | ABBOTT LABORATORIES (US) | 1997-12-02 | — | — | US | disclosed |