⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850806 | 0.82 | CYP4F2 (0.34) | — | |
| SCHEMBL7786273 | 0.76 | — | — | |
| SCHEMBL7786274 | 0.76 | — | — | |
| SCHEMBL7785789 | 0.70 | — | — | |
| SCHEMBL7785787 | 0.70 | — | — | |
| SCHEMBL7785776 | 0.68 | NPSR1 (0.42) | — | |
| SCHEMBL21974585 | 0.68 | NPSR1 (0.42) | — | |
| SCHEMBL7785774 | 0.68 | NPSR1 (0.42) | — | |
| SCHEMBL1336752 | 0.68 | — | — | |
| SCHEMBL1336751 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-B1 | Cyanopyrrolidines useful for the treatment of inter alia metabolic syndrome | SANWA KAGAKU KENKYUSHO CO (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |