Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.54 |
| ▸ | DRD3 | P35462 | 11/20 | 0.54 |
| ▸ | DRD4 | P21917 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134051 | 0.83 | DRD2 (0.53) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL9731853 | 0.82 | DRD2 (0.51) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL3685045 | 0.81 | DRD2 (0.55) | DRD2DRD3DRD4CA1CA2 | |
| Hydrochloric Acid SCHEMBL7737940 | 0.80 | DRD2 (0.54) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL7396762 | 0.79 | DRD2 (0.53) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL7384016 | 0.79 | DRD2 (0.55) | DRD2DRD3DRD4CA1CA2 | |
| Hydrochloric Acid SCHEMBL7385145 | 0.79 | DRD2 (0.47) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL7786290 | 0.78 | DRD2 (0.51) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL8891880 | 0.77 | DRD2 (0.51) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL10507841 | 0.76 | DRD2 (0.57) | DRD2DRD3DRD4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717620-B1 | SUBSTITUTED 2-AMINOTETRALINS | DISCOVERY THERAPEUTICS INC (US) | 2001-10-31 | — | — | EP | disclosed |