Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381770 | 0.94 | MAPT (0.46) | KMT2AMAPTCHRNA7PTPN1TTR | |
| SCHEMBL7796371 | 0.93 | MAPT (0.49) | KMT2AMAPTCHRNA7PTPN1ALDH1A1 | |
| SCHEMBL7796533 | 0.93 | MAPT (0.54) | KMT2AMAPTCHRNA7TTRMAOB | |
| SCHEMBL7786114 | 0.93 | MAPT (0.51) | KMT2AMAPTCHRNA7TTRMAOB | |
| SCHEMBL7796335 | 0.93 | KMT2A (0.51) | KMT2AMAPTCHRNA7PTPN1ALDH1A1 | |
| SCHEMBL7792434 | 0.92 | MAPT (0.51) | KMT2AMAPTCHRNA7PTPN1ALDH1A1 | |
| SCHEMBL7792253 | 0.91 | KMT2A (0.49) | KMT2AMAPTCHRNA7PTPN1TTR | |
| SCHEMBL7796132 | 0.90 | MAPT (0.51) | KMT2AMAPTCHRNA7TTRMAOB | |
| SCHEMBL27564268 | 0.89 | KMT2A (0.46) | KMT2AMAPTCHRNA7PTPN1ALDH1A1 | |
| SCHEMBL7792813 | 0.89 | MAPT (0.49) | KMT2AMAPTCHRNA7TTRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |