SCHEMBL7786841

SCHEMBL7786841

CC(c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.64
ALOX15 P16050 4/20 0.64
ALOX12 P18054 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
HIF1A Q16665 3/20 0.64
CYP1A2 P05177 2/20 0.64
CYP2C19 P33261 2/20 0.64
CYP2C9 P11712 1/20 0.64
TSHR P16473 5/20 0.50
TTR P02766 3/20 0.50
CYP3A4 P08684 3/20 0.50
RECQL P46063 3/20 0.50
ALDH1A1 P00352 2/20 0.50
THRB P10828 3/20 0.46
KIF11 P52732 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
HPGD P15428 4/20 0.40
MAPK1 P28482 3/20 0.40
ESR1 P03372 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142489 0.84 HSD17B10 (0.46) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL13801377 0.84 HSD17B10 (0.64) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL736680 0.82 HSD17B10 (0.61) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL4464101 0.78 HSD17B10 (0.70) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL1595467 0.78 HSD17B10 (1.00) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL9908614 0.77 HSD17B10 (0.54) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL17612792 0.74 HSD17B10 (0.64) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL16150316 0.73 HSD17B10 (0.50) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL9808035 0.73 HSD17B10 (0.50) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A
SCHEMBL837133 0.73 HSD17B10 (0.50) HSD17B10ALOX15ALOX12SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1148934-A1 MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME MESSER GRIESHEIM GMBH (DE) 2001-10-31 EP disclosed
US-6217995-B1 TRANSPARENT POLYCARBONATE OR POLYESTERCARABONATE CONTAINING CYCLIC ALIPHATIC GROUP, HAVING A VISIBLE LIGHT TRANSMITTANCE MORE THAN 80% AND A GLASS TRANSITION TEMPERATURE LESS THAN 80 DEGREE C. EXHIBIT BIREFRINGENCE INDEX LESS THAN 15 NM MITSUBISHI CHEMICAL CORPORATION (JP) 2001-04-17 US disclosed
US-6168649-B1 THIN DISCRIMINATING LAYER SELECTED FROM THE GROUP CONSISTING OF POLYCARBONATE, POLYESTER, AND POLYESTERCARBONATE. MG GENERON, INC. 2001-01-02 US disclosed
WO-2000033949-A1 MEMBRANE FOR SEPARATION OF XENON FROM OXYGEN AND NITROGEN AND METHOD OF USING SAME MESSER GRIESHEIM GMBH (DE) 2000-06-15 WO disclosed
EP-0739879-B1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL CO (JP) 1999-12-22 EP disclosed
EP-0739879-A1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-30 EP disclosed
US-5196531-A Poly(N-cyclic iminoether), process for production thereof, thermosetting composition containing it and thermoset resin TEIJIN LIMITED (JP) 1993-03-23 US disclosed
US-5189094-A Reacting a poly(cyclic iminoether), and ethylenically unsaturated compounds TEIJIN LIMITED (JP) 1993-02-23 US disclosed
EP-0351814-A2 Poly (N-cyclic iminoether), processes for production thereof, thermosetting composition containing it and thermoset resin TEIJIN LIMITED (JP) 1990-01-24 EP disclosed
EP-0336390-A2 Process for producing thermoset resin TEIJIN LIMITED (JP) 1989-10-11 EP disclosed
US-4354994-A Spinning process for antimony oxide/halogenated aromatic polyester composition CELANESE CORPORATION (US) 1982-10-19 US disclosed
US-4355152-A HEAT TREATMENT CELANESE CORPORATION (US) 1982-10-19 US disclosed
US-4346209-A HEAT TREATMENT AT CONSTANT LENGTH FOLLOWED BY TREATMENT WI HOT PERCHLOROETHYLENE CELANESE CORPORATION (US) 1982-08-24 US disclosed
US-4322521-A Process for producing halogenated aromatic polyesters CELANESE CORPORATION (US) 1982-03-30 US disclosed
EP-0007940-A1 SOLUTION POLYMERIZED HALOGENATED POLYESTERS CELANESE CORPORATION (US) 1980-02-20 EP disclosed
US-4150068-A OLIGOMERIC POLYHALOPHOSPHATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-04-17 US disclosed
US-4145218-A AMINO-THIO COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-03-20 US disclosed
WO-1979000071-A1 SOLUTION POLYMERIZED HALOGENATED POLYESTERS CELANESE CORP (US) 1979-02-22 WO disclosed
US-4132705-A Process for preparing a halogenated aromatic polyester having a predetermined molecular weight by solution polymerization technique CELANESE CORPORATION (US) 1979-01-02 US disclosed
US-4066623-A INVERSE INTERFACIAL POLYMERIZATION FOR PREPARING CERTAIN HALOGENATED AROMATIC POLYESTERS CELANESE CORPORATION (US) 1978-01-03 US disclosed