Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595357 | 0.85 | HSD17B10 (0.61) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL9908614 | 0.79 | HSD17B10 (0.54) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL9429452 | 0.78 | CA1 (0.41) | CYP1A2CYP2C9TTRCYP3A4ALDH1A1 | |
| SCHEMBL2415957 | 0.77 | HSD17B10 (0.56) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL1596641 | 0.76 | HSD17B10 (0.61) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL9808125 | 0.76 | FOLH1 (0.40) | HSD17B10ALOX15ALOX12CYP2C19HIF1A | |
| SCHEMBL837133 | 0.76 | HSD17B10 (0.50) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL6555161 | 0.73 | HSD17B10 (0.52) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL7786841 | 0.73 | HSD17B10 (0.64) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 | |
| SCHEMBL13801377 | 0.73 | HSD17B10 (0.64) | HSD17B10ALOX15ALOX12CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |