Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11518915 | 0.83 | MAPT (0.46) | DAOSMN1; SMN2MAPT | |
| SCHEMBL7783961 | 0.75 | CYP19A1 (0.43) | DAOMAPT | |
| SCHEMBL7783987 | 0.75 | DAO (0.50) | DAOSMN1; SMN2TAAR1PTGS2MAPT | |
| SCHEMBL7783554 | 0.73 | DAO (0.52) | DAOGRM2TAAR1 | |
| SCHEMBL5906372 | 0.71 | — | — | |
| SCHEMBL7783960 | 0.70 | DAO (0.55) | DAOTAAR1 | |
| SCHEMBL15563972 | 0.70 | DAO (0.54) | DAOHRH3 | |
| SCHEMBL16968224 | 0.70 | DAO (0.54) | DAOHRH3 | |
| SCHEMBL13315556 | 0.68 | TOP2A (0.37) | GRM2TP53MAPT | |
| SCHEMBL7783967 | 0.68 | DAO (0.33) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144392-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040568-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-07-13 | — | — | WO | disclosed |