Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.36 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218310 | 0.87 | HDAC4 (0.50) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7796571 | 0.82 | HDAC4 (0.46) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL8876764 | 0.81 | HDAC4 (0.43) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL3772653 | 0.81 | HDAC4 (0.44) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7793163 | 0.78 | HDAC4 (0.44) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL5665141 | 0.78 | HDAC4 (0.44) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| Acridan SCHEMBL7793226 | 0.78 | HDAC4 (0.36) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL31613807 | 0.75 | HDAC4 (0.66) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL2989515 | 0.75 | HDAC4 (0.66) | HDAC4HDAC7HDAC5MEN1KMT2A | |
| SCHEMBL7752463 | 0.74 | HDAC4 (0.43) | HDAC4HDAC7HDAC5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | claimed |
| US-5593845-A | BY REACTION WITH PEROXIDES AND PEROXIDASE; DETECTION OF HAPTENS, PROTEINS, ANTIBODIES IN ENZYME IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-01-14 | — | — | US | disclosed |