Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705623 | 0.88 | MEN1 (0.57) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL6705617 | 0.88 | MEN1 (0.57) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| Potassium Ion SCHEMBL6708622 | 0.85 | TDP1 (0.70) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| Potassium Ion SCHEMBL6708624 | 0.85 | TDP1 (0.70) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| Potassium Ion SCHEMBL6708618 | 0.85 | TDP1 (0.70) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL7787101 | 0.82 | MEN1 (0.74) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL11121143 | 0.79 | SHBG (0.51) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL11122760 | 0.78 | CYP19A1 (0.51) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL11743506 | 0.74 | SHBG (0.53) | MEN1KMT2ATDP1SHBGCYP19A1 | |
| SCHEMBL11743496 | 0.74 | SHBG (0.53) | MEN1KMT2ATDP1SHBGCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863760-B1 | USE OF ANTIMINERALOCORTICOID COMPOUNDS AGAINST DRUG WITHDRAWAL SYNDROME | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |
| EP-0055170-B1 | 3-KETO-DELTA-4 OR DELTA-1,4 STEROID DERIVATIVES SUBSTITUTED AT POSITION 7, THEIR PREPARATION, THEIR UTILIZATION AS PHARMACEUTICAL COMPOSITIONS, AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-10-24 | — | — | EP | claimed |