SCHEMBL7787348

SCHEMBL7787348

Cc1nc(C(F)(F)F)c(C(=O)Nc2ccccc2C(C)C)s1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
KDM4E B2RXH2 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
GAA P10253 1/20 0.47
ALDH1A1 P00352 1/20 0.44
RECQL P46063 3/20 0.43
RAB9A P51151 1/20 0.43
NTRK1 P04629 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
HSD11B1 P28845 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786610 0.88 MAPT (0.46) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL13295602 0.87 MAPT (0.46) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL23367943 0.85 MAPT (0.55) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL23367944 0.84 MEN1 (0.56) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL5163362 0.84 MAPT (0.54) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL5165086 0.83 MAPT (0.53) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL13057264 0.83 MAPT (0.44) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL21652164 0.82 MAPT (0.52) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL29584574 0.82 LPAR1 (0.41) MAPTKDM4EHTTSMN1; SMN2TDP1
SCHEMBL28350020 0.82 LPAR1 (0.41) MAPTKDM4EHTTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824099-B1 Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient MITSUI CHEMICALS INC (JP) 2001-11-07 EP disclosed
US-5965774-A CONTROLLING PLANT DISEASES AGAINST BOTRYTIS CINEREA, POWDERY MILDEW, PYRICULARIA ORYZAE OF RICE PLANT MITSUI CHEMICALS, INC. (JP) 1999-10-12 US disclosed
US-5914344-A Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient MITSUI CHEMICALS, INC. (JP) 1999-06-22 US disclosed
EP-0824099-A1 Substituted carboxanilide derivative and plant disease control agent comprising same as active ingredient MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-02-18 EP disclosed