Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23367943 | 0.88 | MAPT (0.55) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL23367944 | 0.87 | MEN1 (0.56) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL5165086 | 0.86 | MAPT (0.53) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL21652164 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL9225609 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL7787348 | 0.84 | MAPT (0.51) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL7458241 | 0.82 | MAPT (0.49) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL13210783 | 0.81 | NTRK1 (0.51) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL12212660 | 0.80 | MAPT (0.54) | MAPTSMN1; SMN2KDM4EHTTTDP1 | |
| SCHEMBL978883 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2KDM4EHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474406-B1 | DISUBSTITUTED THIAZOLYL CARBOXANILIDES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AG (DE) | 2007-03-21 | — | — | EP | disclosed |
| US-7098227-B2 | Disubstituted thiazolyl carboxanilides and their use as microbicides | BAYER CROPSCIENCE AG (DE) | 2006-08-29 | — | — | US | disclosed |
| US-20050143428-A1 | Disubstituted thiazolyl carboxanilides and their use as microbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| EP-1474406-A1 | DISUBSTITUTED THIAZOLYL CARBOXANILIDES AND THEIR USE AS MICROBICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066609-A1 | DISUBSTITUTED THIAZOLYL CARBOXANILIDES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143428-A1 | Disubstituted thiazolyl carboxanilides and their use as microbicides | CX3CR1, MSR1, CD209 | MAPT 4122/4885SMN1; SMN2 4808/4885KDM4E 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.