Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.61 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796736 | 0.80 | HDAC6 (0.60) | HDAC6WDR91KDM1AMCHR1ALDH1A1 | |
| SCHEMBL7867209 | 0.79 | HDAC6 (0.60) | HDAC6KDM1AHDAC8 | |
| SCHEMBL1174257 | 0.76 | HDAC6 (1.00) | HDAC6ALDH1A1POLBPKMNPC1 | |
| SCHEMBL1173937 | 0.75 | HDAC6 (0.80) | HDAC6KDM1ANPC1RAB9A | |
| SCHEMBL7787923 | 0.75 | HDAC6 (0.57) | HDAC6WDR91KDM1AMCHR1ALDH1A1 | |
| SCHEMBL1174246 | 0.74 | HDAC6 (1.00) | HDAC6WDR91KDM1AALDH1A1POLB | |
| SCHEMBL7795830 | 0.73 | HDAC6 (0.64) | HDAC6WDR91KDM1AMCHR1ALDH1A1 | |
| SCHEMBL7797093 | 0.72 | HDAC6 (0.58) | HDAC6WDR91KDM1AALDH1A1POLB | |
| SCHEMBL7796842 | 0.71 | HDAC6 (0.60) | HDAC6KDM1AMCHR1ALDH1A1POLB | |
| SCHEMBL7797020 | 0.71 | HDAC6 (0.57) | HDAC6WDR91KDM1AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |