Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787392 | 0.79 | HDAC6 (0.61) | HDAC6HDAC8KDM1A | |
| SCHEMBL1081728 | 0.78 | HDAC6 (0.88) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1027560 | 0.77 | HDAC6 (0.73) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1264433 | 0.76 | HDAC6 (0.71) | HDAC6HDAC8HDAC3HDAC1KDM1A | |
| SCHEMBL1028087 | 0.76 | HDAC6 (0.93) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1262847 | 0.76 | HDAC6 (0.97) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1264461 | 0.75 | HDAC6 (1.00) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1262890 | 0.75 | HDAC6 (1.00) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1264104 | 0.75 | HDAC6 (0.77) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL1081445 | 0.74 | HDAC6 (0.70) | HDAC6HDAC8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |