Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL616319 | 0.93 | — | — | |
| Ethylene SCHEMBL649443 | 0.88 | — | — | |
| Bromide SCHEMBL7889956 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL1130389 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL5969054 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4443640 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7634884 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3674858 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6304997 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL6751293 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1151019-A1 | GERMANIUM BRIDGED METALLOCENES PRODUCING POLYMERS WITH INCREASED MELT STRENGTH | Univation Technologies LLC (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000040622-A1 | GERMANIUM BRIDGED METALLOCENES PRODUCING POLYMERS WITH INCREASED MELT STRENGTH | UNIVATION TECHNOLOGIES, LLC (US) | 2000-07-13 | — | — | WO | disclosed |
| US-6034192-A | POLYMERIZING ETHYLENE USING COORDINATION CATALYST | UNIVATION TECHNOLOGIES, LLC (US) | 2000-03-07 | — | — | US | disclosed |