Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040340 | 0.85 | CACNA1B (0.69) | CACNA1BMEN1KMT2AYAP1 | |
| SCHEMBL7381620 | 0.83 | CACNA1B (0.57) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL7037543 | 0.81 | CACNA1B (0.60) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL28760866 | 0.80 | CACNA1B (0.53) | CACNA1BJAK2JAK1YAP1STS | |
| SCHEMBL7038257 | 0.78 | CACNA1B (0.51) | CACNA1BMEN1KMT2AJAK2JAK1 | |
| SCHEMBL2195527 | 0.76 | PDE4A (0.53) | YAP1STSGPR119 | |
| SCHEMBL9014040 | 0.76 | KDM1A (0.48) | CACNA1BMEN1KMT2ASTSGPR119 | |
| SCHEMBL23249889 | 0.75 | SMN1; SMN2 (0.58) | MEN1KMT2AJAK2JAK1STS | |
| SCHEMBL19970722 | 0.75 | GPR119 (0.53) | JAK2JAK1YAP1STSGPR119 | |
| SCHEMBL7036969 | 0.74 | MEN1 (0.46) | CACNA1BMEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251918-B1 | FOR THERAPY OF STROKE, CEREBRAL ISCHEMIA, HEAD TRAUMA, OR EPILEPSY | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |