Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785125 | 0.91 | CXCR2 (0.32) | — | |
| SCHEMBL7780331 | 0.89 | ALDH1A1 (0.32) | ALDH1A1LMNAGAA | |
| SCHEMBL7795456 | 0.87 | CXCR2 (0.35) | ALDH1A1LMNAGAA | |
| SCHEMBL7780384 | 0.86 | CXCR2 (0.33) | — | |
| SCHEMBL7780353 | 0.83 | POLB (0.34) | ALDH1A1LMNAGAA | |
| SCHEMBL7787853 | 0.82 | KMT2A (0.38) | ALDH1A1LMNAGAA | |
| SCHEMBL7784926 | 0.82 | KMT2A (0.38) | ALDH1A1LMNAGAA | |
| SCHEMBL7785294 | 0.80 | ALDH1A1 (0.31) | ALDH1A1LMNAGAA | |
| SCHEMBL7787494 | 0.79 | KMT2A (0.38) | ALDH1A1LMNAGAA | |
| SCHEMBL7784925 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |