SCHEMBL7787748

SCHEMBL7787748

CCc1c(Cl)cc(O)c(NC(=O)C(CC)Oc2ccc(C(C)(C)CC)cc2C(C)(C)CC)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.39
KMT2A Q03164 6/20 0.39
MAPK1 P28482 5/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
MEN1 O00255 5/20 0.39
ALDH1A1 P00352 1/20 0.39
ACACB O00763 1/20 0.38
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 4/20 0.33
HTT P42858 3/20 0.33
UBE2N P61088 2/20 0.33
GLA P06280 1/20 0.33
MITF O75030 1/20 0.33
RAD52 P43351 2/20 0.31
STAT3 P40763 1/20 0.31
RCE1 Q9Y256 1/20 0.31
APAF1 O14727 1/20 0.31
HSP90AA1 P07900 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10635099 0.90 NPSR1 (0.40) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL3429177 0.87 KMT2A (0.39) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL14106872 0.83 MAPK1 (0.47) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL11877719 0.82 NPSR1 (0.41) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL10763854 0.82 SMN1; SMN2 (0.51) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL8082860 0.80 KMT2A (0.38) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL11528814 0.80 NPSR1 (0.41) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL8740989 0.79 MAPK1 (0.37) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL12352171 0.79 MEN1 (0.43) NPSR1KMT2AMAPK1SMN1; SMN2MEN1
SCHEMBL7704204 0.79 NPSR1 (0.40) NPSR1KMT2AMAPK1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683427-B1 Blue sensitizing dyes with heterocyclic substituents EASTMAN KODAK CO (US) 2001-11-14 EP disclosed
EP-0679939-B1 Acyl substituted oxonol dyes EASTMAN KODAK CO (US) 2001-11-14 EP disclosed
US-6066443-A PROVIDES GOOD SPEED AND IMPROVED COLOR REPRODUCTION; MAXIMUM BLUE SENSITIVITY AT LESS THAN 485 NM. EASTMAN KODAK COMPANY (US) 2000-05-23 US disclosed
EP-0683427-A1 Blue sensitizing dyes with heterocyclic substituents EASTMAN KODAK COMPANY (US) 1995-11-22 EP disclosed
EP-0679939-A1 Acyl substituted oxonol dyes EASTMAN KODAK COMPANY (US) 1995-11-02 EP disclosed
US-5451494-A Photographic elements containing acyl substituted oxonol dyes EASTMAN KODAK COMPANY (US) 1995-09-19 US disclosed
US-5391474-A Forming emulsion containing silver chloride, washing, sensitizing with gold salt, adding iridium complex containing halogen ligands, adding bromide EASTMAN KODAK COMPANY (US) 1995-02-21 US disclosed
EP-0199290-B1 SILVER HALIDE PHOTOGRAPHIC EMULSION AND PHOTOGRAPHIC MATERIAL CONTAINING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1992-01-22 EP disclosed
US-5043460-A Discoloration inhibition; color photography FUJI PHOTO FILM CO., LTD. (JP) 1991-08-27 US disclosed
US-4917994-A GELATIN SILVER HALIDE EMULSION WITH ACIDIC SURFACE; STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1990-04-17 US disclosed
US-4745050-A Silver halide color photographic material and discoloration inhibitor therefor FUJI PHOTO FILM CO., LTD. (JP) 1988-05-17 US disclosed
US-4735894-A PROJECTION JOINED CRYSTALS OF DIFFERENT HALOGEN COMPOSITIONS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-05 US disclosed
EP-0199290-A2 Silver halide photographic emulsion and photographic material containing the same FUJI PHOTO FILM CO., LTD. (JP) 1986-10-29 EP disclosed