Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | ADH1B | P00325 | 2/20 | 0.40 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | ADH4 | P08319 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216588 | 1.00 | CTSK (0.40) | CTSKCTSLCTSBADH1BADH1C | |
| SCHEMBL11449274 | 1.00 | CTSK (0.40) | CTSKCTSLCTSBADH1BADH1C | |
| SCHEMBL12216583 | 0.98 | CTSK (0.38) | CTSKCTSLCTSBADH1BADH1C | |
| SCHEMBL12216591 | 0.98 | CTSK (0.38) | CTSKCTSLCTSBADH1BADH1C | |
| SCHEMBL10138778 | 0.93 | — | — | |
| SCHEMBL99021 | 0.88 | — | — | |
| SCHEMBL21067333 | 0.88 | — | — | |
| SCHEMBL15173337 | 0.84 | CTSK (0.37) | CTSKCTSLCTSBADH1BADH1C | |
| SCHEMBL2400205 | 0.82 | — | — | |
| SCHEMBL15675604 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837845-B1 | HERPES RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2001-11-28 | — | — | EP | claimed |