Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780352 | 1.00 | MAPK1 (0.45) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7787701 | 1.00 | MAPK1 (0.45) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7784938 | 0.92 | MAPK1 (0.45) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7780356 | 0.92 | MAPK1 (0.45) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7780405 | 0.90 | LMNA (0.48) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7780373 | 0.90 | LMNA (0.48) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7785104 | 0.90 | GAA (0.46) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7785144 | 0.90 | AKR1C3 (0.48) | ALDH1A1LMNAAKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL7788967 | 0.90 | MAPK1 (0.51) | MAPK1NPSR1MAPTALDH1A1NPC1 | |
| SCHEMBL7785483 | 0.89 | MAPK1 (0.47) | MAPK1NPSR1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |