Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37915 | 0.86 | ALDH1A1 (0.42) | TSHRTHRBALDH1A1TDP1 | |
| Ethylene SCHEMBL8679123 | 0.84 | ALDH1A1 (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL4823985 | 0.84 | — | — | |
| SCHEMBL6269152 | 0.84 | — | — | |
| SCHEMBL1057516 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL22017 | 0.84 | — | — | |
| SCHEMBL28226548 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| SCHEMBL8921614 | 0.84 | — | — | |
| Fluoride SCHEMBL8087473 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1CYP3A4 | |
| Acetone SCHEMBL11804126 | 0.82 | TSHR (0.48) | TSHRTHRBALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | claimed |
| EP-1152242-A1 | CONTAINER FOR IMMUNOLOGIC ASSAY | SUMITOMO BAKELITE CO., LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |