Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.63 |
| ▸ | CASP6 | P55212 | 5/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 3/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393721 | 0.81 | NSD2 (0.74) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL1377131 | 0.77 | NSD2 (1.00) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL7712968 | 0.76 | NSD2 (0.74) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL3894493 | 0.75 | NSD2 (0.78) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL8568600 | 0.75 | NSD2 (0.54) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL8109724 | 0.75 | NT5E (0.74) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL9093564 | 0.73 | CASP6 (0.62) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL589899 | 0.73 | CASP6 (0.62) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL8976412 | 0.73 | NSD2 (0.66) | NSD2CASP6DUSP3PTPN5PTPN11 | |
| SCHEMBL9614638 | 0.73 | NSD2 (0.65) | NSD2CASP6DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888406-B1 | AZO COMPOUNDS | AVECIA LTD (GB) | 2001-12-12 | — | — | EP | disclosed |