Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14359629 | 0.94 | BCL9 (0.64) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL7161403 | 0.90 | BCL9 (0.71) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL3919600 | 0.90 | BCL9 (0.76) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL531007 | 0.90 | BCL9 (0.76) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL531155 | 0.89 | BCL9 (0.73) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL570540 | 0.89 | BCL9 (0.73) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL530771 | 0.89 | BCL9 (0.73) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL7079988 | 0.89 | BCL9 (0.73) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL957930 | 0.87 | BCL9 (0.81) | BCL9CTNNB1KMT2AGAAPKM | |
| SCHEMBL16915260 | 0.86 | BCL9 (0.66) | BCL9CTNNB1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147076-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | Amersham Pharmacia Biotech K.K. (JP) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043355-A1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-07-27 | — | — | WO | disclosed |