SCHEMBL7787953

SCHEMBL7787953

CCOC(=O)C(F)(I)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPT P10636 4/20 0.39
HIF1A Q16665 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PKM P14618 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.37
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123913 0.81
Ammonia Solution, Strong SCHEMBL8163563 0.79 ALDH1A1 (0.42) ALDH1A1POLBNPSR1MAPTHIF1A
SCHEMBL16481576 0.77
SCHEMBL20319592 0.76 ALDH1A1 (0.43) ALDH1A1POLBNPSR1MAPTHIF1A
SCHEMBL196352 0.76 ALDH1A1 (0.43) ALDH1A1POLBNPSR1MAPTHIF1A
SCHEMBL4857911 0.76 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5613290 0.75
SCHEMBL27889607 0.75 ALDH1A1 (0.48) ALDH1A1POLBNPSR1MAPTHIF1A
SCHEMBL1979744 0.75 ALDH1A1 (0.48) ALDH1A1POLBNPSR1MAPTHIF1A
SCHEMBL4392350 0.75 ALDH1A1 (0.48) ALDH1A1POLBNPSR1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103127877-B A kind of fluorine-containing surfactant and preparation method thereof SHANDONG DONGYUE POLYMER MATERIAL CO., LTD. (CN) 2015-09-09 CN disclosed
CN-103193904-B A kind of dispersion method prepares the method for fluoropolymer SHANDONG DONGYUE POLYMER MATERIAL CO., LTD. (CN) 2015-09-09 CN disclosed
CN-103193904-A Method for preparing fluorine-containing polymer through dispersion method SHANDONG DONGYUE POLYMER MAT 2013-07-10 CN disclosed
CN-103127877-A Fluorine-containing surfactant and preparation method thereof SHANDONG DONGYUE POLYMER MAT 2013-06-05 CN disclosed
EP-0842160-B1 FLUORINATED ALKENYLTRIAZINES AND THEIR USE AS CROSSLINKING AGENTS DU PONT (US) 2001-11-14 EP disclosed
EP-0822175-B1 Hydrogen-containing fluorosurfactant and its use in polymerisation DU PONT (US) 2001-05-16 EP disclosed
US-5763552-A Hydrogen-containing flourosurfacant and its use in polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-09 US disclosed
EP-0842160-A1 FLUORINATED ALKENYLTRIAZINES AND THEIR USE AS CROSSLINKING AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-05-20 EP disclosed
EP-0822175-A2 Hydrogen-containing fluorosurfactant and its use in polymerisation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-04 EP disclosed
WO-1997005122-A1 FLUORINATED ALKENYLTRIAZINES AND THEIR USE AS CROSSLINKING AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-13 WO disclosed