Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6817667 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6817652 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7788513 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9422133 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4800699 | 0.70 | — | — | |
| SCHEMBL8157639 | 0.67 | — | — | |
| SCHEMBL813561 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6812899 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL3894364 | 0.61 | — | — | |
| SCHEMBL31542512 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639579-B1 | Preparation of metallocenes | ALBEMARLE CORP (US) | 2001-10-31 | — | — | EP | disclosed |
| US-5455333-A | Preparation of metallocenes | ALBEMARLE CORPORATION (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0639579-A2 | Preparation of metallocenes | ALBEMARLE CORPORATION (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5276220-A | Aluminoxanes and actinides as catalysts and polyolefins | ETHYL CORPORATION (US) | 1994-01-04 | — | — | US | disclosed |