Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 4/20 | 0.53 |
| ▸ | LGALS1 | P09382 | 4/20 | 0.53 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.53 |
| ▸ | LGALS7; LGALS7B | P47929 | 3/20 | 0.53 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.40 |
| ▸ | SELP | P16109 | 6/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305543 | 1.00 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL7796841 | 1.00 | LGALS9 (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL12139436 | 0.88 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCHRNA7 | |
| SCHEMBL10005364 | 0.88 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCHRNA7 | |
| SCHEMBL14586557 | 0.88 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCHRNA7 | |
| SCHEMBL18510805 | 0.88 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCHRNA7 | |
| SCHEMBL12595097 | 0.87 | POLB (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL14356291 | 0.87 | POLB (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL4736023 | 0.87 | POLB (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB | |
| SCHEMBL4570559 | 0.87 | POLB (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794194-B1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0794194-A1 | A process for the preparation of 2'-deoxy-2'-halocoformycins or stereoisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1997-09-10 | — | — | EP | disclosed |