SCHEMBL7788481

SCHEMBL7788481

N=C(N)NCCC[C@H](NC(=O)CNCc1cccc(Cl)c1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.57
C3AR1 Q16581 7/20 0.44
GID4 Q8IVV7 1/20 0.44
F7 P08709 1/20 0.42
CHRM2 P08172 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788471 1.00 FOLH1 (0.57) FOLH1C3AR1GID4F7CHRM2
SCHEMBL7786281 0.89 FOLH1 (0.43) FOLH1C3AR1
SCHEMBL7785788 0.89 FOLH1 (0.43) FOLH1C3AR1
SCHEMBL7786368 0.89 FOLH1 (0.49) FOLH1C3AR1
SCHEMBL7786354 0.89 FOLH1 (0.49) FOLH1C3AR1
SCHEMBL7786343 0.87 FOLH1 (0.43) FOLH1C3AR1F7
SCHEMBL7786351 0.87 FOLH1 (0.43) FOLH1C3AR1F7
SCHEMBL7788448 0.86 C3AR1 (0.44) FOLH1C3AR1
SCHEMBL7788437 0.86 C3AR1 (0.44) FOLH1C3AR1
SCHEMBL4738184 0.84 FOLH1 (0.62) FOLH1C3AR1GID4CHRM2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010056185-A1 C3A receptor ligands LEE DENNIS (US) 2001-12-27 US claimed
EP-1017664-A1 C3A RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 2000-07-12 EP claimed
WO-1999015490-A1 C3A RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 1999-04-01 WO claimed
US-20010056185-A1 C3A receptor ligands LEE DENNIS (US) 2001-12-27 US disclosed
EP-1017664-A1 C3A RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 2000-07-12 EP disclosed
WO-1999015490-A1 C3A RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 1999-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056185-A1 C3A receptor ligands C3AR1, C5AR1, C5AR2 FOLH1 1373/4885C3AR1 1/4885GID4 1811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.