Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.49 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786354 | 1.00 | FOLH1 (0.49) | FOLH1C3AR1ALDH1A1RAB9AOPRK1 | |
| SCHEMBL7788471 | 0.89 | FOLH1 (0.57) | FOLH1C3AR1 | |
| SCHEMBL7788481 | 0.89 | FOLH1 (0.57) | FOLH1C3AR1 | |
| SCHEMBL7790387 | 0.87 | HDAC1 (0.42) | FOLH1C3AR1ITGB3NPY1RNPY2R | |
| SCHEMBL7790393 | 0.87 | HDAC1 (0.42) | FOLH1C3AR1ITGB3NPY1RNPY2R | |
| SCHEMBL7785788 | 0.86 | FOLH1 (0.43) | FOLH1C3AR1NPY1RSHMT1NPY2R | |
| SCHEMBL7786281 | 0.86 | FOLH1 (0.43) | FOLH1C3AR1NPY1RSHMT1NPY2R | |
| SCHEMBL7790277 | 0.86 | ITGB3 (0.41) | FOLH1C3AR1ITGB3NPY1RSHMT1 | |
| SCHEMBL7786343 | 0.86 | FOLH1 (0.43) | FOLH1C3AR1NPY1RNPY2RNPY4R | |
| SCHEMBL7790269 | 0.86 | ITGB3 (0.41) | FOLH1C3AR1ITGB3NPY1RSHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010056185-A1 | C3A receptor ligands | LEE DENNIS (US) | 2001-12-27 | — | — | US | disclosed |
| EP-1017664-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015490-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056185-A1 | C3A receptor ligands | C3AR1, C5AR1, C5AR2 | FOLH1 1373/4885C3AR1 1/4885ALDH1A1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.