Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | CRHBP | P24387 | 2/20 | 0.81 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.67 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.67 |
| ▸ | ITGAL | P20701 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353510 | 1.00 | SMN1; SMN2 (0.81) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL8947096 | 1.00 | SMN1; SMN2 (0.81) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL23658082 | 0.98 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL11505282 | 0.98 | LMNA (0.85) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL11505281 | 0.98 | LMNA (0.85) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL30143827 | 0.98 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL14161716 | 0.96 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL14488910 | 0.95 | LMNA (0.81) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL8346859 | 0.95 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL15381227 | 0.93 | LMNA (0.77) | SMN1; SMN2LMNACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626406-B1 | Process for preparing thermoplastic polyesters possessing high stability in the molten state | GROUP S R L P (IT) | 2001-10-31 | — | — | EP | disclosed |
| EP-0684285-A1 | Process for the preparation of compatible thermoplastic compositions from polyesters and polycarbonates | ENICHEM S.p.A. (IT) | 1995-11-29 | — | — | EP | disclosed |
| EP-0626425-A2 | Compatible thermoplastic compositions based on polyesters and polycarbonates | ENICHEM S.p.A. (IT) | 1994-11-30 | — | — | EP | disclosed |
| EP-0626406-A2 | Thermoplastic polyesters possessing high stability in the molten state | ENICHEM S.p.A. (IT) | 1994-11-30 | — | — | EP | disclosed |