SCHEMBL7788795

SCHEMBL7788795

CCC(Cl)(Cl)OC(Cl)(Cl)CC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237227 0.83 TSHR (0.33) TSHRTDP1ALDH1A1
SCHEMBL16231395 0.81
SCHEMBL1225110 0.72
SCHEMBL6902215 0.72 FDPS (0.31)
SCHEMBL11612106 0.72
SCHEMBL6426802 0.69 TSHR (0.31) TSHRTDP1ALDH1A1
SCHEMBL2781735 0.67
SCHEMBL1656377 0.67 FDPS (0.36) TSHRTDP1ALDH1A1
SCHEMBL4887580 0.67
SCHEMBL933531 0.67 TSHR (0.38) TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3996272-A Method for preparing pentachloroacetone and dichloroacetic acid from isopropyl ethers THE DOW CHEMICAL COMPANY (US) 1976-12-07 US claimed
EP-3194352-B1 PROCESS FOR HYDROGENATING DICHLOROISOPROPYL ETHER DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-10 EP disclosed
US-9758454-B2 Process for hydrogenating dichloroisopropyl ether DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-12 US disclosed
EP-3194352-A1 PROCESS FOR HYDROGENATING DICHLOROISOPROPYL ETHER Dow Global Technologies LLC (US) 2017-07-26 EP disclosed
US-20170204028-A1 PROCESS FOR HYDROGENATING DICHLOROISOPROPYL ETHER DOW GLOBAL TECHNOLOGIES LLC (US) 2017-07-20 US disclosed
WO-2016044009-A1 PROCESS FOR HYDROGENATING DICHLOROISOPROPYL ETHER DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-24 WO disclosed
US-8957258-B2 BIS(1,1-Dichloro-3,3,3-trifluoropropyl) ether and process for preparing the same KANTO DENKA KOGYO CO., LTD. (JP) 2015-02-17 US disclosed
EP-1140752-A1 PROCESS FOR PREPARING CHLOROHYDRINS THE DOW CHEMICAL COMPANY (US) 2001-10-10 EP disclosed
WO-2000035846-A1 PROCESS FOR PREPARING CHLOROHYDRINS THE DOW CHEMICAL COMPANY (US) 2000-06-22 WO disclosed
US-6051742-A Process for preparing chlorohydrins THE DOW CHEMICAL COMPANY (US) 2000-04-18 US disclosed
EP-0855377-A1 Process for the selective removal of organic nitrates from a halogenated organic stream UOP (US) 1998-07-29 EP disclosed
US-5578740-A Process for preparation of epoxy compounds essentially free of organic halides THE DOW CHEMICAL COMPANY (US) 1996-11-26 US disclosed
US-5552037-A Process for the treatment of two halogenated hydrocarbon streams UOP (US) 1996-09-03 US disclosed
EP-0682100-A1 Suppression of carbonaceous deposits in a process for hydrotreating an organic feedstock containing unstable olefinic compounds UOP (US) 1995-11-15 EP disclosed
US-4496752-A REACTING TERTIARY ALCOHOL WITH CHLORINE TO GIVE TERTIARY ALKYL HYPPOCHLORIDT, REACTING WITH UNSATURATED COMPOUND TO GIVE CHLOROHYDRIN, THEN REACTING WITH TERTIARY ALCOHOL THE LUMMUS COMPANY (US) 1985-01-29 US disclosed
US-4298758-A Process for the production of propylene glycol esters from chloropropyl ethers THE DOW CHEMICAL COMPANY (US) 1981-11-03 US disclosed
US-4166894-A QUATERNARY AMMONIUM COMPOUNDS OR POLYMERS HAVING AMIDE GROUPS CALGON CORPORATION (US) 1979-09-04 US disclosed
US-4075136-A ELECTROCONDUCTIVE COATING CALGON CORPORATION (US) 1978-02-21 US disclosed
US-4053525-A HYDROLYZING A CHLOROHYDRIN; ALKALI METAL CARBONATE CATALYST SHELL OIL COMPANY (US) 1977-10-11 US disclosed
US-4008133-A ANND CHLORINE THE LUMMUS COMPANY (US) 1977-02-15 US disclosed