SCHEMBL7788985

SCHEMBL7788985

C/C=C/CCc1ccc(C=O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.41
ALDH1A1 P00352 6/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A3 P47895 2/20 0.39
ALDH3A1 P30838 1/20 0.39
TYR P14679 1/20 0.38
CYP2A13 Q16696 1/20 0.38
GPR52 Q9Y2T5 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH5A1 P51649 1/20 0.37
ABAT P80404 1/20 0.37
KMT2A Q03164 1/20 0.34
EPHX2 P34913 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
KCNH2 Q12809 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7788986 1.00 CYP2A6 (0.41) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL7792190 0.82 ALDH1A1 (0.42) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL7792194 0.82 ALDH1A1 (0.42) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL10743219 0.79 CYP2A6 (0.44) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL10743234 0.79 CYP2A6 (0.44) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL13367648 0.79 CYP2A6 (0.42) CYP2A6ALDH1A1MAPTHPGDLMNA
SCHEMBL10009929 0.79 HRH3 (0.43) GPR52KCNH2
SCHEMBL7791455 0.78 GRIN2D (0.45) ALDH1A1MAPTLMNASMN1; SMN2GPR52
SCHEMBL7791461 0.78 GRIN2D (0.45) ALDH1A1MAPTLMNASMN1; SMN2GPR52
SCHEMBL7791458 0.78 GRIN2D (0.45) ALDH1A1MAPTLMNASMN1; SMN2GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed