Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789228 | 1.00 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7793263 | 0.91 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7793268 | 0.91 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7783421 | 0.86 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7783424 | 0.86 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7783428 | 0.84 | NFE2L2 (0.53) | NPC1RAB9ASMN1; SMN2NFE2L2POLB | |
| SCHEMBL7783430 | 0.84 | NFE2L2 (0.53) | NPC1RAB9ASMN1; SMN2NFE2L2POLB | |
| SCHEMBL7793377 | 0.83 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7791889 | 0.83 | GRIN2D (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D | |
| SCHEMBL7791884 | 0.83 | GRIN2D (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6010642-A | LIGHT SCATTERING LIQUID CRYSTAL DISPLAY | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |