Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786342 | 1.00 | RARB (0.54) | RARBNR5A1CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL16436176 | 0.85 | RARB (0.58) | RARBNR5A1CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL8396365 | 0.84 | TSHR (0.58) | RARBNR5A1CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL30996184 | 0.83 | TAAR1 (0.53) | CYP2D6CYP2C19TAAR1TP53 | |
| SCHEMBL1521996 | 0.83 | TSHR (0.65) | NR5A1CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL4663093 | 0.83 | TSHR (0.65) | NR5A1CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL1522035 | 0.83 | TSHR (0.65) | NR5A1CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL9149380 | 0.83 | TSHR (0.65) | NR5A1CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL7176783 | 0.83 | CYP2D6 (0.59) | RARBNR5A1CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9152810 | 0.83 | LTA4H (0.70) | RARBNR5A1CYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |