Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.52 |
| ▸ | ACHE | P22303 | 12/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29752682 | 0.77 | KDM4E (0.50) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL6930623 | 0.76 | KDM4E (0.50) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL2812104 | 0.76 | KDM4E (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL11070778 | 0.75 | KDM4E (0.58) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL11608873 | 0.75 | CA12 (0.42) | BCHEACHEMEN1KMT2A | |
| 1-Ethylquinolonium SCHEMBL11069884 | 0.74 | KDM4E (0.50) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL241884 | 0.73 | CA1 (0.52) | KMT2A | |
| SCHEMBL15661681 | 0.70 | GAA (0.50) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL10602153 | 0.70 | STAT3 (0.42) | KDM4E | |
| Water SCHEMBL7788572 | 0.69 | CA1 (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |