SCHEMBL7789562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6352647	0.89	PTGS2 (0.80)	PTGS2PTGS1ABCB11ALDH1A1
	SCHEMBL8924564	0.88	PTGS2 (0.64)	PTGS2PTGS1CYP2C9
	SCHEMBL3249718	0.88	PTGS2 (0.95)	PTGS2PTGS1ABCB11ALDH1A1CYP2C9
	SCHEMBL6339240	0.88	PTGS2 (1.00)	PTGS2PTGS1ABCB11ALDH1A1PDPK1
	SCHEMBL3243184	0.88	PTGS2 (0.82)	PTGS2PTGS1ABCB11ALDH1A1
	SCHEMBL213150	0.88	PTGS2 (1.00)	PTGS2PTGS1ABCB11ALDH1A1CYP2C9
	SCHEMBL212658	0.88	PTGS2 (1.00)	PTGS2PTGS1ABCB11ALDH1A1PDPK1
	SCHEMBL215341	0.88	PTGS2 (1.00)	PTGS2PTGS1ABCB11ALDH1A1CYP2C9
	SCHEMBL6339195	0.88	PTGS2 (0.90)	PTGS2PTGS1ABCB11ALDH1A1CYP2C9
	SCHEMBL5425139	0.87	PTGS2 (0.83)	PTGS2PTGS1ABCB11ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.