⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688531 | 0.98 | THRB (0.32) | — | |
| SCHEMBL1444616 | 0.98 | THRB (0.32) | — | |
| SCHEMBL7788052 | 0.98 | THRB (0.32) | — | |
| SCHEMBL15157434 | 0.98 | THRB (0.32) | — | |
| SCHEMBL3806298 | 0.98 | THRB (0.32) | — | |
| SCHEMBL1149531 | 0.94 | TSHR (0.31) | — | |
| SCHEMBL1322852 | 0.89 | TSHR (0.36) | — | |
| SCHEMBL1321394 | 0.87 | TSHR (0.35) | — | |
| SCHEMBL367166 | 0.87 | TSHR (0.35) | — | |
| SCHEMBL7175291 | 0.87 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136896-A | Graft copolymers containing polydiorganosiloxane and polybutylene grafts | DOW CORNING CORPORATION (US) | 2000-10-24 | — | — | US | claimed |
| EP-0768862-B1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | PROCTER & GAMBLE (US) | 2001-10-17 | — | — | EP | disclosed |
| US-6165455-A | Personal care compositions containing thermoplastic elastomeric graft copolymers | THE PROCTER & GAMBLE COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-6136896-A | Graft copolymers containing polydiorganosiloxane and polybutylene grafts | DOW CORNING CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |
| EP-0768862-A1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996000562-A1 | PERSONAL CARE COMPOSITIONS CONTAINING THERMOPLASTIC ELASTOMERIC GRAFT COPOLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |