Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.80 |
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285014 | 0.98 | HAO1 (0.83) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL1194076 | 0.91 | HAO1 (0.96) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL5474445 | 0.89 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL5468904 | 0.89 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL8741845 | 0.89 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL2528845 | 0.89 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL8074587 | 0.89 | HAO1 (1.00) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL7798107 | 0.86 | HAO1 (0.65) | HAO1CES1CES2KMT2AMAPT | |
| SCHEMBL247453 | 0.83 | HAO1 (0.68) | HAO1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL534933 | 0.80 | CES1 (0.58) | HAO1CES1CES2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808849-B1 | Process for the production of ethylenic polymers | SHOWA DENKO KK (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6326443-B1 | COORDINATION POLYMERIZATION CATALYST | SHOWA DENKO K.K. (JP) | 2001-12-04 | — | — | US | disclosed |
| US-6011127-A | CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. | SHOWA DENKO K.K. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0931797-A1 | PROCESS FOR PREPARING ETHYLENE POLYMER AND CATALYST USED THEREFOR | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0763550-B1 | Ethylenic polymerization catalyst | SHOWA DENKO KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5723399-A | CHROMIUM COMPOUND, ALUMOXANE, TRANSITION METAL COMPOUND | SHOWA DENKO K.K. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |
| EP-0763550-A1 | Ethylenic polymerization catalyst | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-03-19 | — | — | EP | disclosed |