⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533285 | 0.67 | — | — | |
| SCHEMBL12019246 | 0.67 | — | — | |
| SCHEMBL7043489 | 0.67 | — | — | |
| SCHEMBL1768253 | 0.67 | — | — | |
| SCHEMBL6992454 | 0.67 | — | — | |
| Hymexazol SCHEMBL8756453 | 0.65 | — | — | |
| SCHEMBL11443231 | 0.62 | — | — | |
| SCHEMBL2310979 | 0.62 | — | — | |
| SCHEMBL9260906 | 0.62 | KDM4E (0.37) | — | |
| SCHEMBL18687389 | 0.61 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922316-A | Fto inhibitor | 北京生命科学研究所 | 2018-04-17 | — | — | CN | disclosed |
| US-6251898-B1 | Medical use of fluorenone derivatives for treating and preventing brain and spinal injury | QUESTCOR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |