Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767722 | 0.76 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9674913 | 0.71 | KDM4E (0.40) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL573342 | 0.71 | CA2 (0.40) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8130541 | 0.71 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9673163 | 0.70 | KDM4E (0.36) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9891488 | 0.68 | MEN1 (0.44) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL12602883 | 0.68 | CYP2C19 (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7982124 | 0.67 | ALDH1A1 (0.34) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL18884374 | 0.67 | EPHX2 (0.42) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9892806 | 0.67 | KDM4E (0.37) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434175-A | PARASITICIDES, INSECTICIDES AND MITICIDES | ROUSSEL UCLAF (FR) | 1995-07-18 | — | — | US | disclosed |
| US-5360906-A | N-(3-halo-5-isoxazolylmethyl)-2-nitromethylene- and -2-nitroimino-imidazolines and pyrimidines; aminoalkylation, cyclization | SHELL RESEARCH LIMITED (GB) | 1994-11-01 | — | — | US | disclosed |
| EP-0555931-A1 | Isoxazole derivatives and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-18 | — | — | EP | disclosed |